Some patients have severe, aggressive forms of acne which merit separate discussion. These include acne conglobata, acne fulminans, Gram-negative folliculitis, pyoderma faciale and vasculitic acne. Notes on their treatment are included here.

Dandruff, like many dermatological symptoms, is not easy to assess clincially but it is probably more prevalent in patients with acne..

Subjects with 'teenage' acne probably do not show an obvious increased incidence of other androgenmediated signs such as hirsuties , irregular periods or infertility but no good study exists to demonstrate this. If correct, this clinical supposition then supports the view that the average acne patient is not an 'endocrinological misfit'.

The seborrhoea of acne thus probably represents either an altered androgen metabolism in the sebaceous gland or a state of end-organ hyperresponsiveness in such patients..

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Aggressive and severe acne .-::78890::-.